Dwyane Wade will miss his 27th game of the season, sitting Wednesday against the Grizzlies because of a hamstring issue.
Wade has battled a number of issues and injuries this season, but has missed the last eight because a sore hamstring.
The Heat are 17-9 without Wade in the lineup this season. Ray Allen is expected to start in his place.
The Heat will also be missing Udonis Haslem, Chris Anderson and Greg Oden. Currently, the Heat are just one game ahead of the Pacers in the loss column.
